Minerals for Arthritis

Mineral supplements for arthritis

In the previous article we saw Vitamins for arthritis research were made a few years ago regarding the need for certain vitamins to improve the symptoms of arthritis. Then treat minerals for arthritis and related diseases.

Copper and arthritis

An important test, which were analyzed in 240 patients with arthritis (of bone, rheumatoid and 'rheumatism') with copper bracelets, bangles bracelets placebo without (all of them were crossed) indicated that copper bracelets were effective in alleviating their symptoms (11). The average loss of copper in the bracelet was 13 mg per month of use. The status of those who habitually wore copper bracelets to retirárseles them worse.

In investigations carried out on more than 1000 patients, it was found that copper salicylate was orally administered more effective in the relief of rheumatoid arthritis and other rheumatic conditions, only the copper (as copper acetate) or salicylic acid alone. The most effective treatment was intravenous copper salicylate short term (12).

Selenium and Rheumatoid Arthritis

In rheumatoid arthritis, and in all age levels, the levels of selenium and glutathione peroxidase in the blood plasma were found low compared with those of control patients (13,14). These findings represent the first evidence regarding a possible therapeutic use of selenium in rheumatoid arthritis. Selenium therapy does not improve this state, although blood levels of this mineral return to normal. Therefore, although the administration of selenium may not lead to an improvement, a serious deficiency of selenium present in these states could give rise to additional problems, if it is not corrected. As regards Osteoarthritis is a clinical trial with selenium-ACE (144 mcg of selenium more vitamins A, C and E) in which thirty patients with this condition in the knee or hip were treated daily with product for 6 months in a double-blind control research. Both groups, the active and placebo showed a trend toward improvement, but no significant difference was found between them in the evaluation of pain or stiffness. The authors (15) conclude that selenium does not show very useful in osteoarthritis.

Other minerals for arthritis

Boron and arthritis

Little evidence is available on the effectiveness of boron in humans as a treatment for arthritis, but the existing ones are highly satisfactory. J.H. Hall et al published in the Journal of P'harmaceutical Society, 1980 (16), that the boron analogs of the amino acids (ie chelates) are effective in reducing the symptoms of rheumatoid arthritis. Subsequently, in 1981 and 1984, R.E. Newnham informed the Australian Academy of Sciences and the Conference of Trace Elements Group, New Zealand, respectively, that daily supplementation with 9 mg of boron produced improvements on several criteria, in both types of arthritic patients (17, 18). Somehow, this aspect is effective in activating the body steroid hormones which are known beneficial in the treatment of arthritis.

Dr. Neil Ward, University of Surrey, communicated in 1987 (19) bones of rheumatoid arthritic patients contains boron levels significantly lower than those found in control specimens. A newer test (20) gives results of a double-blind control trial comparing an intake of 6 mg of boron per day, relative to placebo, in the treatment of osteoarthritis. Only 15 patients took part in the test (5 of them had left for various reasons), but 50% of those treated with boron arthritis improved, while only 10% of those treated with placebo had the same results. Of those who completed the trial, 71% improved while receiving boron. This test was essentially just a pilot test, which indicated that the amount of boron was a safe dose administered (during the 8-week test) and possibly beneficial against osteoarthritis. Boron was administered as borax (25 mg). More tests are needed with larger numbers of patients, so that boron may become considered an anti-arthritis supplement.

Sulfur and osteoarthritis

It is attributed to the mineral property to be beneficial in the treatment of osteoarthritis. It raised the suspicion that sulfur deficiency was critical at the level found that this mineral was under the nails of patients with osteoarthritis. When given colloidal sulfur or sulfur baths taking these accuse relief (are elevated sulfur levels in the blood), but these tests, made during the decade of the '30s have never been played. It has also been argued successfully in cases of patients with rheumatoid arthritis (21,22).

Iron

Iron supplementation in rheumatoid arthritis is highly controversial, with different evidence for and against.

Manganese and rheumatoid arthritis

The influence of manganese has been suggested because the total presence of this nutrient in the body is low in cases of rheumatoid arthritis, but levels return to normal when starting achieved satisfactory therapy supplementation (23). However, no tests performed exclusively with manganese.

Zinc and rheumatoid arthritis

Zinc levels are reduced in patients with rheumatoid arthritis, but did not show any relationship with disease severity. In recent years there have been four trials using zinc Rtrouinatoide Arthritis, two positive and two negative. In a study of psoriatic arthritis, joint pains were significantly reduced after daily intake of 220 mg zinc sulphate, 3 times daily for 6 weeks. Subsequently improvement was observed in morning stiffness and general status. Although dimmed arthritic symptoms, there was no any effect on the problem of the skin (24). In the second investigation positive, 12 patients were resistant to other therapies were administered 150 mg of elemental zinc daily for 12 weeks while 12 others are only given a placebo. After all these, 24 received zinc for 12 weeks. Treatment with this mineral found significant improvements in joint swelling, morning stiffness, in the time to walk and in subjective symptoms (25).

Two other studies have shown that improvement, when there is little. The first, in which 22 patients with rheumatoid arthritis were given 220 mg zinc sulphate 3 times daily, or placebo for 6 months. Although subjective improvement was observed during this period in 6 patients, was followed by a decline (26) when zinc therapy was interrupted. In the second test was not obtained any response to zinc (27). It has been suggested that zinc can produce improvements to reduce high levels of copper is known to exist in many patients with arthritis (28).

Source: DR. Leonard Mervyn - LAMBERTS

REFERENCES

11. WALKER. W.R. and Keats, D. M. An investigation of the therapcutic value of the 'copper trtacelee. Dermal assimilation uf copper in arthritichteumatoid conditions. Agents and Actions. 6. 454. 1976.
12. SORENSON, J.R.J. and HANGARTER, W. Treatment of rheumatoid and degenerate: diseascs with copper eomplexes: A review with emphasis one copper-salicylate. Inflammation 2217. 1977.
13: JOHANSON, V. and others. Nutritional status in girls with juvenile arthritis chmnic. Human.Nutr: Clin.Nutr. 40C. 57, 1986.
14, - TARE '. V. and others. Low Levels selenium in severe rheumatoid arthritis. Scand.J.Rheumatol. 14, 97, 1985.
15, HILL, J. and BIRD. H.A. Failure of Selenium-ACE Improve what osteoarthritis. Br.J.Rhewnatol. 29.21!, 1990.
16. HALL, J. H. J.Pharm.Soc. 69. 1025, 1980.
17, Newnham, R. E. in 'Trace Element Metabolism in Man and Animals-'4 editor J. McC.Howell. J.M. Gowthorne and C.L. White. Aust join Acad. Canberra. 1981, p.400-402.
18. Newnham. R.E. 'Boron is essential - it corrects and prevention,: arthritis'. Presented in New Zealand Trace Element Group. Massey University, Palmerston Nortkikilt * Zealand. 7 to 8 August 1984.
19. WARD, Ni. J.RadioalialyiNuc.Chem. Articles 110 (2). 633. 1987.
20. TRAVERS. R.L. and others. Boron and Arthrins: I heard the result doublehlind pilot study. iNutr.Med. 1. 127, 1990.
21. NEL1GAN. A.R. and SALT, H.B. Sulphur in rheumatoid arthritis. Lance) 2.2181. 1934.
22, Woldenberg. S.C. 'The tn: atment of the Arthritis cabbage with colloidal sulfur. J.SoutheroMed.Asoc. 28. 875, 1935.
23. Cotzias, G.C. and others. Slow turnover of manganese in active rheumatoid arthritis and acceleration by prednisone. J. Clininvest. 47, 992. 1968.
24. Clemmensen. 0.). and others. Psoriatic arthritis oral zinc sulphate TREATED WITH. Brit.J.Dermatol. 103, 411. 1980.
25: SIMK1N, P.A. Oral zinc sulphate in rhcumatoid arthritis. Lance) 2, 539, 1976.
26. Rasker, .1.1. and KARDAUN, SIL Lack of effect of zinc sulphate heneficial in rheumatoid anhritis. Scand.J.Rheumatol. I I. 168, 1982,
27. JOB, C. and others. Zinc sulpham in the tmatment of rheumatoid arthritis. Arthritis Rheum. 23. 1408, 1980.
28. PFEIFFER. C. Zinc and other mieronutrients. Kens Publishing, 1978. p.51.

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