Natural Remedies for Arthritis

Remedies for Arthritis -1

DLPA and Arthritis

One of the absolutely positive cases have been published concerning a woman whose history of rheumatoid arthritis went back to 18 years ago (39).

Obtained her dramatic relief in patent inflammation and swelling that had, after only 7 days of treatment with this amino acid. Besides pain relief, there was also a significant improvement in joint flexibility. The dosage used was 750 mg, 15-30 minutes before meals 3 times daily. The positive effects can take up to 21 days, but you can double the dose for 3 weeks, if therapy is ineffective low power.

Histidine is another amino acid that is attributed to the effect of relief for patients with rheumatoid arthritis. Test was used in a very limited dose of 4.5 g per day, appreciating a better response in patients with active and prolonged symptoms of the disease (40).

Omega-6 (Evening Primrose Oil) and Arthritis

This oil seems to offer hope for the treatment of symptoms of rheumatoid arthritis but, so far, no evidence that may suggest that patients benefit from Osteoarthritis resulting substance.

The original studies, with 1 gram of primrose oil, 4 times a day for 3 months, indicating that:

  • It is relatively ineffective in patients treated with higher doses of corticosteroids to trivial or anti-inflammatory drugs, but may allow a reduced dosage after 1-3 months.
  • The effects are only visible after 4-12 weeks;
  • Some patients who accuse the best long-term response transient relapse during the first 1-2 weeks, and
  • The development of the disease can be arrested, in fact, in some patients (42).

Three further tests confirm the benefits of evening primrose oil. In a study of 20 patients, when administered in combination with cofactors zinc, niacin and pyridoxine ascorbic acid, evening primrose oil proved to be as effective as non-steroidal analgesics (43).

The Lancet publishes another test, in which 2.1 grams of evening primrose oil were positive after 3 months of therapy (44). In the latest research, conducted double-blind controlled, this oil alone or combined with small amounts of fish oil, provided relief in approximately 92% of treated cases. About 60% of them, or oils could stop treatment with anti-inflammatory drugs, and another 25% was reduced dosage of such drugs.

Supplementation with evening primrose oil and fish oil together yields better results than single primrose oil. Borage oil (another source of gamma linoleic acid) at a dose of 1 g per day was effective in tests. 1 \ 16 However, without thereby try to downplay the effect of omega-6 fatty acids, it should be noted that, in another test, 45% of participating patients, who were treated with placebo paraffin liquid plus vitamin E, improved and maintained their improvement for a year. Of course, it is debatable whether this is really a placebo placebo, since vitamin E alone has some anti-arthritic properties.

Omega-3 (fish oils) and Arthritis

Like the type of omega-6 fatty acids omega-3 have been tested only in patients with rheumatoid arthritis, but not in cases of osteoarthritis. In controlled research, 17 patients received a diet high in polyunsaturated fatty acids (PUFA) by low-fat diet saturation, and supplemented with 1.8 g of EPAMHA day, while 20 patients received a control diet stream , Western-type plus placebo oil capsules. After 12 weeks, the EPA group showed a significantly reduced morning stiffness that in cases with placebo (in patients with placebo, this was precisely the symptoms that had worsened). The joints also presented less softening. As the capsules were removed and stopped oil diet high in polyunsaturated fatty acids (PUFA), all patients worsened, with increases in pain and stiffness (46).

In a second study, we compared a dose of 1.8 g of EPA and placebo in 19 patients who were also treated with nonsteroidal anti-inflammatory drugs. After 6 weeks, the fish oil group showed a significant reduction in the incidence of joint pain, compared with controls. Although relief disappeared drug therapy withdraw anti-inflammatory drugs, those taking fish oil were displayed an improvement by comparison with controls. This evidence suggests an anti-inflammatory effect of fish oil (47).

At present, the relationship between the metabolism of the fish oil and arthritis is considered as only a theory based. Some studies have shown some alteration in the inflammation response after ingestion of fish oil, and prostaglandins produced from factors EPA / DHA seem to be involved in the perception of pain, but these studies have been main -mind with animals or in vitro only. However, it is still evident that a combination of omega-3 to omega-6 has proven more effective in treating human patients with omega-6 alone and therefore omega -3 contribute to some extent with some type of anti-arthritic action.

Other remedies for arthritis

Yucca saponin extract

In a double-blind pilot study (48) on 149 patients, 88 of whom had osteoarthritis and rheumatoid arthritis 61, were treated with placebo or yucca saponin extract for periods ranging from 1 week to 15 months before retesting. 61% of those treated with cassava had less swelling, pain and stiffness, compared with 22% of those treated with placebo. Some improved within days, others for weeks and others after 3 months or more. It has been estimated that the active components are saponins, which was not absorbed, but ran through the gastrointestinal tract.

Acacia greggii

Although there are many anecdotal reports on the effectiveness of Acacia greggii in alleviating the symptoms of arthritis, the only acceptable research is a test conducted on 43 patients, which was conducted over a period of 60 days (49). Eighteen of them had ankylosing spondylitis, while the remainder were divided almost equally between osteoarthritis and rheumatoid arthritis. Efficacy was assessed by periods of 8, 15, 30 and 60 days, according to the criteria of pain intensity, functional ability and the time required for the elimination of stiffness. The dosage was 1.5 g of this supplement daily.

In two thirds of patients, we obtained more than 50% reduction in pain, with only 11% who experienced no improvement. The analgesic effect was seen after 8 days of therapy, the responders as well as the reduction in stiffness. This trial was not placebo controlled. However, there is no doubt about the effectiveness of this supplement, as it was observed some reduction in pain in 88% of patients, the functional capacity showed an improvement in 84% and there was a reduction in stiffness 86% of patients.

Superoxide Dismutase

Superoxide dismutase has been considered beneficial in osteoarthritis (50), but only when injected. Similar results have been observed in rheumatoid arthritis (51).

Bromelain

Bromelain (a proteinase from pineapple), when presented in an enteric-coated form (20-40 mg. 3-4 times a day) has beneficial results in rheumatoid arthritis. The residual was reduced joint swelling and joint mobility increased, with only 14% of patients who were not with any improvement. It i did the study on 29 patients, and one of the positive aspects observed was the reduction in steroid therapy in some of them. Which also suffered from gout, no relief for this state.

CONCLUSIONS

It is a fact that none of the natural supplements used against arthritic conditions has been subjected, as if it were the other widely used synthetic drugs, extensive clinical testing. The one that has been investigated is the green mussel extract, but even in this case, the results are controversial, mainly due to differences in methodologies and treatment time, and perhaps this is due to the absence of controls quality that serve to evaluate the characteristics of each preparation. None of the active entities has been measured, and thus is not available any information to compare one batch to another. Similar considerations apply also to the extracts of Acacia greggii and cassava, although in the latter, the saponin content can be determined.

Just as different patients respond differently to the wide variety of medications available, it is likely that responses to natural supplements are equally personal and linked to the individuality of each. This could explain the variability of the responses, and the large number of natural medicines to which is attributed the ability to provide relief. Similarly, the placebo response is very high in these conditions. The evaluation of the responses in both rheumatoid arthritis and in osteoarthritis is difficult, though, in rheumatoid arthritis, certain blood tests establish a relationship with the improvements of the state. Many patients can claim relief, even though conventional clinical trials indicate no response. These anecdotal reports can not be ignored. So the natural arthritis treatments remain under investigation.

References

39. HOPKINS. P. Ehronic Phenylalaninc and relief of pain. Anaholism 4. (2) 302, 1985.
40. PINALS. R.S. and others. Treatmcnt of rheumathoid with L-histidine arthritis: A randomized, placebo-controlted. hlind double trial. J.Rheumah 1. 4 (4), 414.1977
41. Broadhurst, A.D. Tryptophan and rheumatic diseases. Brit.Med.J., August 13, 1977, P456.
42. Horrobin. DF The imponance of gamma-linolenic acid and prostaglandin E. in human nutrition and medicine. i.Holisttc Med 3, 118. 1981.
43 HANSEN. TM. and others. Treatment of rheumatoid anhritis with pmstaglandin The preeursors cis-linoleic acid and gamma-linolenic ActD. Scand.J.Rheum. 12, 85, 1983.
44. McCORMICK. J.N. and others. Immunosuppressive effect of linoleic acid. Lancet 2, 5 () 8. 1977.
45. L1 WAN PO, A. Evening Primrose Oil. The Pharmaceutical Journal. 1st June 1991 P.676-678.
46. KREMER, J.M. and others. Effect of manipulation of dietary fatty acids cm manifestations of rheumatoid artyritis elinical. Lancet 1, 184, 1985.
47. SPERLING. R.I. Med.World News July 14, 1988.
48. BINGHAM, R. and others. Yucea plant saponin in the management of anhritis. J.Applied Nutr. 27, 45, 1975.
49. Pinget. M. and Lecomte. A. The Effects of Harpagophytum degenerative Arkoeaps in rheumatology. Pub by Arkophanna Laboratories. Industrial Estate. Berck I '. 06,511 cars. Estnksburgo. 1985.
50. Lund-Olesen. K. and Menander, K.B. Orgotein: A ncw ann-inthunmatory metalloprotein drug: Preliminary evaluation of clinical ellieacy and safety in degenerative joint disease. Curr.Ther.Res 6.7 (16. 1974.
51. GOEBEL, K. M. and others. Orgotein Intrasynovial therapy in rheumatoid arthritis. Lanero I, 1015, 1981.
52. COHEN. A. and Goldman. Bromelains therapy in rheumatoid arthritis. PennsylMed.J. 67, 27. 1964.

Source: DR. Leonard Mervyn - Lamberts

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