Vitamin E and cancer

Many tests and research suggests that free radicals often play a role in the process of cancer. Therefore, vitamin E and other antioxidants to control free radicals are expected to contribute to the inhibition of cancer.

This hypothesis has been confirmed in preliminary tests on isolated tissues and in animals, but indications of the benefits of vitamin E in humans have only been obtained from epidemiological investigations. However there are indications of the existence of a correlation between low levels of this vitamin in blood plasma and the incidence of certain cancers. These include breast cancer in women (1), stomach cancer (2), colon cancer (3), lung cancer (4), neck (5), mouth and pharynx (6).

Oral leukoplakia (white plaques on the mucous membranes) is a precancerous condition that can lead to cancer of the mouth and throat. One study has shown that 400 IU of alpha-tocopherol administered twice daily for 24 weeks served to roll back the state in 46% of the investigated patients with positive histological responses in 31% of total patients.

1 .- Knekt, P., Internat. J. Epidemiol. 17, 281-286, 1988
2 .- Knekt, P. et al. Int J. Cancer 42, 846-850, 1988
3 .- Knekt, P. et al. J. Epidemiol. 127, 28-42, 1988
4 .- Comstock, G.W. et al. J. Clin. Nourishes 53, 13-20, 1991
5 .- Palan, P.R.., Et al Nutr. Cancer, 15, 13-20, 1991
6 .- Gridley, G. et al. J. Epidemiol. 135, 1083.1092, 1992

Related Topics
* Vitamin E. Wheat germ oil
* Vitamin E protects the heart. Free radicals and LDL
* Vitamin E or tocopherol
* Free radicals. Food Antioxidants and ORAC
* Cancer. Theories about its cause. Treatments with natural medicine

*Automatic Translation