Vitamins for Arthritis

Supplements for Arthritis

It seems that there are many natural remedies for arthritis as varieties of that condition. In this comprehensive report, Dr. Leonard Mervyn refers only to rheumatoid arthritis, osteoarthritis and ankylosing spondylitis, which are the three most common arthritic conditions. Of these, osteoarthritis is one that is affecting many people lately.

Although the research presented here are getting on in years, however, we consider interesting to know not only the effort made in natural medicine to investigate and test their remedies and supplements, but in publicizing alternative for those who want another type of conventional therapy.

Osteoarthritis is defined as a chronic disease that affects most notably the weight bearing joints of the body. It is characterized by the destruction of joint cartilage, the disproportionate growth of bone, with proliferating formations and loss of functional capacity. It is almost universal among people over 40 years and is considered caused by degenerative changes.

Rheumatoid Arthritis is defined as a syndrome characterized by chronic nonspecific inflammation but symmetrical peripheral joints, with the potential result of the progressive destruction of the joint and its surrounding areas. It is generally considered to be due to an antigen-antibody reaction, and can erupt at any age.

Ankylosing Spondylitis affects mainly young people (20-40 years) and is characterized by inflammation of the spine and peripheral joints greater.

A summary of natural supplements that are used for these conditions.

Nicotinamide and Osteoarthritis

Used primarily in osteoarthritis. Studies by Kaufman on 663 patients (1) showed that those treated with a daily dose of 3-6 grams per day showed an increase in the mobility of the joints, and reduction of stiffness of the deformity thereof, with pain relief. These findings were confirmed by Hoffer, who highlight the fact that although the relief is usually immediate, long-term improvement can only be obtained with prolonged therapy. In 1983 (2), Kaufman confirmed that with nearly 30 years experience, nicotinamide has been effective in osteoarthritis.

Pantothenic acid and Osteoarthritis

Research on animals suggests that pantothenic acid deficiency induces symptoms of Osteoarthritis. These findings lead to the clinical testing the vitamin B group, in rheumatoid arthritis and in osteoarthritis. An initial investigation (3) has shown that 12.5 mg twice daily results in a limited improvement variable Osteoarthritis, (starting aponerse apparent within 1-2 weeks. These effects disappear with the interruption of the supplementation. The further investigation (4) would be a kind of double blind control on nearly 100 patients with arthritis (63% with osteoarthritis). Dosing was initiated with 500 mg a day, before rising to 500 mg of pantothenate Calcium, 4 times a day. After 2 months, there were no significant reductions in morning stiffness or the degree of disability or the experimental group or the control group, but both groups showed a significant relief of pain. No However, we found evidence that RA patients had apparently improved more than others. encouraging results were obtained in Rheumatoid Arthritis using calcium pantothenate. clinical studies indicate that both oral and intramuscular injection of this vitamin reduce symptoms. In all cases, this relief has been associated with increased levels of vitamin B in blood.

Ascorbic acid and osteoarthritis

Animal tests with guinea pigs (which require a dietary source of vitamin C) showed that low vitamin intakes (2-4 mg daily) induced the classic signs of osteoarthritis. Those who received 150 mg per day not only had lower arthritic changes, but also a much lower erosion of cartilage and smaller changes around joints (5). Gout, another of arthritic diseases can improve with 4 grams of vitamin C a day. It works by stimulating the excretion of uric acid by the kidneys (6). No controlled human studies have been performed on the action of vitamin C in Osteoarthritis, but in vitro responses of human cartilage cells indicate that their healthy state depends on the concentrations of ascorbic acid above the norm.

In the case of rheumatoid arthritis, in blood plasma and leukocytes, ascorbic acid levels are significantly reduced. It suggests that higher intakes of this vitamin should make up these levels and as a result, relieve arthritis, which seems to be the cause of increased destruction of vitamin C (7.8).

The Bloflavonoides, such as quercetin and catechin possess in vitro suggest that play a role in the treatment of rheumatoid arthritis, but there is no clinical evidence of this.

Vitamin E and Arthritis

Vitamin E possesses the property of inhibiting prostaglandin certain inflammatory and therefore would be expected to mitigase arthritic pain, just as the anti-inflammatory steroids. An important research pilot, with strict control on 29 patients, indicates that 600 mg of tocopherol yield results superior to placebo in terms of its effects on osteoarthritis pain (9). The confirmation was established by further research, in 1984 (5). No research has been made comparable with rheumatoid arthritis, but communication in the sense that the blood levels of vitamin E are low in this state, and then the vitamin supplementation provides some relief of symptoms (10) .

Source: DR. Leonard Mervyn - LAMBERTS


1. KAUFMAN. W. The use of vitamin therapy concomitaras heard what eertain reverse aging. J.Am.Geriatr.Soc. 3927. 1955.
2. KAUFMAN. W. Niacinamide. A most neglected vitamin. J.Int.Acad.Prev.Mtx.I. Winter 1983.
3. Annand, J.C. Pantothenie acid and osteoarthritis. Lamed 2. 1168, 1963.
4 PRACTMONER GENERAL RESEARCH GROUP. Calcium pantothenate in anhritic conditions. Practitioner 224, 208, 1980.
5. SCHWARTZ. E.R. The modulauon heard ostcoarthritie vitamins C and development by E. Int.J.Vitand Nutr.Res.Stipl. 26. 141, 1984.
6. STEIN, H. B. and others. Ascorbic acid-induced uricosuria: A consiNuence of megavitamin therapy. Ann.IntiMixl. 84 (4). 385, 1976.
7. MULLEN, Ay WILSON.C.W.M. The metalxilism of ascorbic acid in rheumataid anhritis. Proc.Nutr.Sci. 35, 8A, 1976.
8. ROBERTS. P. and others. Cite vitando inflammaúon. Med.Bio1.63, 88, 1984.
9, MACHTEY. I. and Ouaknine, L. Tocopherol in ostcoarthritis: A controlled study piles. J.Am.Geriatr.Soc. 26, 328, 1978.
10, MACHTEY. I. Vitamin E in arthritis. Arthritis and Rheumatism 34 (9) 1205, 1991.

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