AMG 531. Definition

Medical Definition: AMG 531

Drug used to treat patients with immune thrombocytopenic purpura (ITP) who do not improve with other forms of treatment. In the case of ITP, the immune system destroys platelets (cells that make blood clot). AMG 531 is being studied as a way to treat low platelet counts caused by chemotherapy. The drug binds to the thrombopoietin receptor and causes the bone marrow to make more platelets. In addition, AMG 531 is being studied in the treatment of myelodysplastic syndromes (a group of diseases for which bone marrow does not produce enough healthy blood cells). A type of thrombopoietin agonist. Also called Nplate and romiplostim.

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