Alkylating. Definition

Medical Definition: Alkylating

Drugs that work by directly attacking the DNA of a cell. Although they can operate at any time of the cell cycle are more effective for the synthesis of DNA. Are used to treat Hodgkin's disease, lymphoma, chronic leukemia and some lung carcinomas, breast, prostate and ovary. Examples of drugs in this category are: cyclophosphamide, mechlorethamine and cisplatin (Platinol).

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