Bence-Jones proteinuria. Definition

Medical Definition: Bence-Jones proteinuria

Presence of light chains, kappa or lambda monoclonal globulin in the urine of patients who present with multiple myeloma (plasmacytoma). Nephropathy is associated with myeloma, related, in part, with the tubular reabsorption of these chains, and is an element of poor prognosis of myeloma.

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