Collins solution. Definition

Medical Definition: Collins solution

Preservation solution for organs for intravascular infusion, that was a breakthrough in transplantation, because it was achieved in several hours longer ischemic time tolerated by the organs, especially the kidney, which can reach up to 24 hours. Its composition is similar to intracellular fluid: poor chlorine and sodium, rich in potassium, phosphorus and glucose, and pH and osmolality similar to plasma. With this composition, and his administration less than 5 º C, reduces intracellular acidosis and edema produced by ischemia. Since its first description in 1969, until the appearance of the solution at the University of Wisconsin in 1988, has been the most used. See the removal of organs, perfusion, preservation, transplant.

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