Differentiation. Definition

Medical Definition: Differentiation

The process by which cells acquire a certain form and function during embryonic development or the life of a multicellular organism, specializing in one cell type. The differentiation is usually inversely related to the proliferative capacity of cells, so cancer cells undergo a process of dedifferentiation. In cancer, refers to the mature (developed) the cancer cells of a tumor. Differentiated tumor cells resemble normal cells tend to grow and spread at a slower rate than tumor cells undifferentiated or poorly differentiated, lacking structure and function of normal cells and grow uncontrollably.

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