Extravasation. Definition

Medical Definition: Extravasation

Exit or escape of intravenous fluid (blood, lymph or other fluid) into the perivascular space, driven by factors specific to the glass, or from accidental displacement of the cannula beyond the site of venipuncture, as an anticancer drug, from a blood vessel or tube into the surrounding tissue. The surrounding tissues in which the poison enters have a low buffering capacity and dilution of the same, allowing its aggressive action persists, causing serious injury dependent on the toxic properties and the amount of drug extravasated. Also used to describe the movement out of the cells in a blood vessel into tissue inflammation or metastasis (spread of cancer).

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