Fluorescence In Situ Hybridization. Definition

Medical Definition: Fluorescence In Situ Hybridization

A technique used to observe the genes or chromosomes in cells and tissues. Added to the cells or tissue pieces of DNA prepared in the laboratory containing a fluorescent dye and placed on a glass slide. When these pieces of DNA bind to specific genes or areas of chromosomes on the slide, light when viewed under a microscope with a special light. Also called FISH.

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