IL-1. Definition

Medical Definition: IL-1

It belongs to a group of related proteins made by leukocytes (white blood cells) and other body cells. Mainly macrophages, a type of white blood cells, produce IL-1 and helps another type of white blood cells, lymphocytes, fight infections. It also helps leukocytes pass through the walls of blood vessels to sites of infection and causes fever by affecting areas of the brain that control body temperature. There are two forms of IL-1 alpha and beta, which act the same way. The IL-1 produced in the laboratory is used in the treatment of cancer as a biological response modifier to boost the immune system. The IL-1 is a type of cytokine. Also called interleukin-1.

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