Kidney preservation. Definition

Medical Definition: Kidney preservation

It consists of renal perfusion with preservation solution during the extraction and storage in this solution at 4 ° C in a container with ice. Its aim is to prevent ischemic damage to the kidney, maintain aerobic metabolism, providing glucose metabolic contribution, to prevent cell swelling, change the levels of calcium, treat reperfusion injury, etc.. It also allows to make the tissue typing, the selection and preparation of the recipient, the kidney to transport, etc. There are many different preservation solutions such as Euro-Collins, Wisconsin solution, isotonic citrate solution, etc. The most common method of preservation is that of hypothermic storage, but it is possible to aerobic hypothermic continuous perfusion. It is desirable that the cold ischemia time is minimized, and less than 24 hours to facilitate the early or immediate function of renal graft.

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