Activating peptide pituitary adenylate cyclase. Definition

Medical Definition: activating peptide pituitary adenylate cyclase

38-amino acid polypeptide isolated from bovine hypothalamus, which stimulates adenylate cyclase activity at the pituitary, adrenal and pancreatic acini. Although its physiological role is not well established, besides having a significant vasodilator effect, stimulatory effects have been reported in the secretion of insulin and glucagon, vasopressin and aldosterone in man.

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