Cold ischemia time. Definition

Medical Definition: cold ischemia time

Interval in hours between organ perfusion with preservation solution cool to 4 º C, and declamping blood on the receiver (off the blood of the recipient by the donor organ, after completion of the anastomosis venous and arterial .) The prolonged cold ischemia time exceeding 24 hours is associated with an increased risk of early graft dysfunction. In heart transplantation, liver, pancreas and lung cancer should not exceed four or eight hours.

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