Crescents. Definition

Medical Definition: crescents

Process and extracapillary proliferation in the glomeruli, which take the form of epithelial crescents, and is characteristic of rapidly progressive glomerulonephritis. It consists of a proliferation of epithelial cells, polymorphonuclear leukocytes, lymphocytes, macrophages and fibrin. Can be massive and involve the whole glomerular tuft, which is retracted and collapsed. Evolve to a progressive fibrosis of the crescents and glomerular sclerosis, this phase being indicative of poor prognosis kidney.

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