Disequilibrium syndrome. Definition

Medical Definition: disequilibrium syndrome

Set of systemic symptoms (nausea, vomiting, restlessness, headache) and neurological (rare and severe type seizures, lethargy and coma), associated with electroencephalographic changes that occur during dialysis or shortly after the end of the session. Suspected to be due to an acute increase in brain water content (cerebral edema) or because of acute changes in pH of cerebrospinal fluid. It is more common in patients with acute uremia, dialysis treated aggressively. Provided, in part, dialysis solutions, with high levels of sodium and high in sugar and soft sessions (less time or less energetic).

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