Insulin tolerance test. Definition

Medical Definition: insulin tolerance test

Decrease in circulating glucose induced by an intravenous injection of insulin as a diagnostic test is used to stimulate the secretion of growth hormone, adrenocorticotropin hormone (ACTH), cortisol and prolactin. The most commonly used dose is 0.1 units of regular insulin per kilogram of weight. It requires a reduction in blood glucose below 40 mg% to give validity to the test. Is indicated in the diagnosis of deficiency of growth hormone, as well as in the hypofunction of the hypothalamic-pituitary-adrenal.

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