Vitamin E. Antioxidant and heart

Vitamin E is an antioxidant, and one of its functions as such is to destroy or control free radicals that occur naturally in the human body, and, if left uncontrolled, can damage tissues and organs .

Free radicals are also present in polluted atmospheres (smoke snuff is one of their richest sources) and also occur naturally in food digestion. Fats are particularly vulnerable to attack by free radicals and by its solubility in fats, vitamin E should be considered the main protective agent of the fatty parts of the body.

Free radicals and heart disease
The accumulation of fatty deposits in blood vessels, and particularly in the heart, it is believed at present due to attacks by free radicals on the fat normally present in the blood. This condition is called atherosclerosis, and the likelihood of its development depend on the extent of damage caused by free radicals on the Low Density Lipoprotein (LDL = Low Density Lipoproteins) contained in the blood. LDL is an important goal, and oxidizing LDL, produced by free radicals, leading to formation of potentially dangerous cells are called foam cells (endothelial cells swollen and vacuoles filled with lipid inclusions, which are characteristic of certain alterations in the metabolism of fats). These are the precursors of fatty deposits lodged in blood vessel walls and ultimately cause atherosclerosis. Currently, this is only a hypothesis, but the limited tests and investigations to date suggest that this is a plausible explanation.

Vitamin E and heart protection
The comments we provide evidence that antioxidants such as vitamin E can:
* Protect against LDL oxidation.
* May reduce the rate of oxidizing LDL uptake by other cells.
* Have the ability to reduce foam cell formation.
* They also slow the development of fatty deposits in artery walls.

In vitro investigations have shown that vitamin E protects against cellular oxidation of LDL for a period of 24 hours, and that the addition of extra vitamin E further extends this protection. The greater the amount of vitamin E, the better the protection.

Vitamin E and epidemiological
Most of the evidence for the efficacy of vitamin E for these disease processes stems from epidemiological investigations. They show that the inhabitants of the geographical areas where the concentration of vitamin E in blood plasma are low have a mortality rate from coronary heart disease higher. This relationship has spoken with other micronutrients such as selenium, vitamin A or vitamin C. According to a study in Poland, the levels of vitamin E in plasma sanguíneoson significantly lower in patients with angina than in healthy controls. One reason of the fact that Scotland has the highest incidence of coronary heart disease across the UK may lie in the high intake of grains not comprehensive (no vitamin E) and the low intake of fruits and vegetables (high content of vitamin E).

Women and vitamin E
Women could also benefit from high intakes of vitamin E. In a study of a group of 87,000 women in the United States, the risk of coronary heart disease proved to be a 36% lower in women receiving more than 100 mg. of vitamin E daily, compared with only thrived purely dietary sources. After two years of treatment with dietary supplements, the risk was halved.

These tests represent only a fraction of the epidemiological investigations suggest that vitamin E exerts a protective action on the heart. However, absolute proof must be sought in investigations in which intervention is administered vitamin E. Such research has already started today.

Related topics:

Wheat germ oil. Vitamin E
Free radicals. Food Antioxidants and ORAC
Vitamin E or tocopherol

*Automatic Translation